WebSep 30, 2011 · cause was reduced in the ticagrelor group when compared to the clopidogrel group (4.5% vs. 5.9%, respectively; P<0.001). There was no difference in the rates of major bleeding between the ticagrelor group and the clopidogrel group (11.6% vs. 11.2%, respectively; P=0.43). However, ticagrelor was associated with a higher rate of … WebOct 11, 2024 · Ticagrelor is a prescription drug. It comes as an oral tablet. Ticagrelor oral tablet is available as the brand-name drug Brilinta.It’s also available as a generic drug.

Antiplatelet medications Heart and Stroke Foundation

WebBrilinta (ticagrelor) is an antiplatelet drug used to prevent heart attack while lowering the risk of stroke and other heart-related problems. Brilinta is a brand-name prescription drug that's manufactured by AstraZeneca. On … Ticagrelor, sold under the brand name Brilinta among others, is a medication used for the prevention of stroke, heart attack and other events in people with acute coronary syndrome, meaning problems with blood supply in the coronary arteries. It acts as a platelet aggregation inhibitor by antagonising the P2Y12 … See more In the US, ticagrelor is indicated to reduce the risk of stroke in people with acute ischemic stroke or high-risk transient ischemic attack. In the EU, ticagrelor, co-administered with acetylsalicylic acid … See more Contraindications to ticagrelor are active bleeding, increased risk of bradycardia, concomitant therapy of ticagrelor and strong cytochrome P-450 3A (CYP3A4) inhibitors and moderate or severe hepatic impairment due to the risk of increased exposure to ticagrelor. See more Inhibitors of the liver enzyme CYP3A4, such as ketoconazole and possibly grapefruit juice, increase blood plasma levels of ticagrelor and consequently can lead to bleeding and other adverse effects. Ticagrelor is a weak CYP3A4 inhibitor and is known to … See more Comparison with related drugs With clopidogrel The PLATO trial concluded superiority of ticagrelor compared to clopidogrel in reducing the rate of death from vascular causes, MI, and stroke in people presenting with … See more The common adverse effects are increased risk of bleeding (which may be severe) and shortness of breath (dyspnoea). Dyspnoea is usually transient and mild-to-moderate in severity, with a higher risk at < 1 month, 1–6 months and >6 months of follow … See more Mechanism of action Like the thienopyridines prasugrel, clopidogrel and ticlopidine, ticagrelor blocks adenosine diphosphate (ADP) receptors of subtype See more Ticagrelor is a nucleoside analogue: the cyclopentane ring is similar to the sugar ribose, and the nitrogen rich aromatic ring system resembles the See more auto glass st john's nl

Ticagrelor: Uses, Interactions, Mechanism of Action - DrugBank

WebOct 12, 2024 · Ticagrelor is used together with aspirin to lower your risk of having a stroke or serious heart problems after you've had a heart attack or severe chest pain . … WebAug 23, 2024 · Antiplatelet drugs work to make your platelets less sticky and thereby help prevent blood clots from forming in your arteries. Aspirin is an antiplatelet drug that may be used. P2Y12 receptor blockers are another group of antiplatelet drugs. This group of drugs includes: clopidogrel, ticlopidine, ticagrelor, prasugrel, and cangrelor. WebCOMMON BRAND NAME(S): Brilinta. WARNING: Ticagrelor may cause serious (sometimes fatal) bleeding. Before taking this medication, tell your doctor your medical history, especially about any bleeding problems. … lbp jai